【目的】 运用数据挖掘技术探析庞鹤教授治疗淤积性皮炎的用药规律。【方法】 收集2019年6月至2024年6月期间庞鹤 教授在北京中医药大学东方医院门诊治疗淤积性皮炎的有效病例的处方数据，运用Excel表创建数据库，采用SPSS 25.0统计 软件和SPSS Modeler 18.0软件进行药物的用药频次、性味归经分析和关联规则分析以及高频药物的聚类分析。【结果】 共纳入 中药处方107首，涉及中药140味。使用频次居前10位的药物分别为当归、苍术、桂枝、丹参、黄芪、川芎、赤芍、地龙、 土鳖虫、黄柏；使用频次 ≥ 20次的高频药物共38味。药物的四气以温性为主，五味以辛味为主，主要归肝经、脾经。关联 规则分析得到关联性较高的药对为当归-川芎、丹参-赤芍、当归-赤芍，聚类分析得到4个聚类方。【结论】 庞鹤教授认为淤 积性皮炎以气虚水停、血虚生风、肌肤失养为本，辨证以气血为要，治疗以益气养血、和营通脉、祛风除湿之法，随症兼 用化瘀养阴、化浊解毒之法，体现其基于整体观而调和阴阳的临证思路。

Objective To analyze the medication patterns of Professor Pang He in treating stasis dermatitis using data mining techniques. Methods From June 2019 to June 2024，the prescription data of effective cases of stasis dermatitis treated by Professor Pang He in the outpatient clinic of Dongfang Hospital Beijing University of Chinese Medicine were collected. A database was established using Excel. SPSS 25.0 and SPSS Modeler 18.0 were employed to analyze the occurrence frequency of herbs，the distribution of herbal properties，flavors and meridian tropisms， and association rules of the herbs， as well as the cluster analysis on high-frequency herbs. Results A total of 107 Chinese herbal prescriptions were included，involving 140 distinct herbs. The top 10 herbs by frequency of use were Angelicae Sinensis Radix，Atractylodis Rhizoma，Cinnamomi Ramulus，Salviae Miltiorrhizae Radix et Rhizoma， Astragali Radix， Chuanxiong Rhizoma， Paeoniae Radix Rubra， Pheretima， Eupolyphaga Steleophaga，and Phellodendri Chinensis Cortex. Thirty-eight herbs were identified as the high-frequency herbs （occurrence frequency ≥20）. The herbs were often warm in nature and pungent in flavor，and usually have the meridian tropism of liver meridian and spleen meridian. Association rule analysis identified highly correlated herb pairs， including Angelicae Sinensis Radix-Chuanxiong Rhizoma， Salviae Miltiorrhizae Radix et RhizomaPaeoniae Radix Rubra， and Angelicae Sinensis Radix-Paeoniae Radix Rubra. Cluster analysis yielded four distinct clusters of herbs. Conclusion Professor Pang He posits that the fundamental pathogenesis of stasis dermatitis lies in qi deficiency leading to fluid retention， blood deficiency generating wind， and consequent malnourishment of the skin. His differentiation of syndromes stresses on qi and blood. The treatment principles focus on supplementing qi and nourishing blood，harmonizing nutritive qi and unblocking vessels，and dispelling wind and eliminating dampness， which are supplemented as necessary by the methods of removing stasis and nourishing yin， and resolving turbidity and removing toxins. The approach reflects Professor Pang’s clinical philosophy of harmonizing yin and yang based on a holistic medical perspective.

R275.9

国家自然科学基金项目（编号：81873373）