【目的】 观察穴位埋线联合中脘刺络放血治疗肝胃不和型慢性非萎缩性胃炎（CNAG）的临床疗效。【方法】 选取2023年 4月至2024年10月中山陈星海中西医结合医院门诊收治的80例明确诊断为肝胃不和型CNAG患者为研究对象。按随机数字 表将患者随机分为观察组和对照组，每组各40例。观察组给予穴位埋线联合中脘刺络放血治疗，对照组给予普通针刺治疗。 共治疗2个月。治疗2个月后，评价2组临床疗效。观察2组患者治疗前后中医证候积分的变化情况以及胃黏膜评分的情况。 比较 2组患者治疗前后汉密尔顿焦虑量表（HAMA）和汉密尔顿抑郁量表（HAMD）评分的变化情况。【结果】（1）研究过程中， 观察组失访1例，对照组失访2例。最终观察组39例、对照组38例纳入疗效统计。（2）观察组愈显率为79.49%（31/39），对照 组愈显率为 13.16%（5/38），观察组疗效明显优于对照组，差异有统计学意义（P＜0.05）。（3）治疗后，2组患者各项中医证候 积分及总积分均明显改善（P＜0.05），且观察组在改善中医证候积分方面明显优于对照组，差异有统计学意义（P＜0.05）。（4） 治疗后，2 组患者胃黏膜评分明显改善（P＜0.05），且观察组在改善胃黏膜评分方面明显优于对照组，差异有统计学意义 （P＜0.05）。（5）治疗后，2组患者 HAMA、HAMD 评分均明显改善（P＜0.05），且观察组在改善 HAMA、HAMD 评分方面明显 优于对照组，差异有统计学意义（P＜0.05）。【结论】 穴位埋线联合中脘刺络放血治疗肝胃不和型 CNAG，能明显改善患者的 临床症状，缓解患者的焦虑抑郁情绪，改善患者胃黏膜的炎症状态，临床疗效显著。

Objective To observe the clinical efficacy of acupoint catgut embedding combined with bloodletting pricking at Zhongwan（CV12） point in treating chronic non-atrophic gastritis （CNAG） of liver-stomach disharmony type. Methods Eighty patients diagnosed with CNAG of liver-stomach disharmony type were recruited from the Outpatient Department of Zhongshan Chenxinghai Hospital of Integrated Traditional Chinese and Western Medicine between April 2023 and October 2024. Participants were randomly divided into an observation group and a control group （n=40 each） using a random number table. The observation group received acupoint catgut embedding combined with bloodletting pricking at Zhongwan point， while the control group received conventional acupuncture. The treatment duration was 2 months for both groups. After treatment，clinical efficacy was evaluated. Changes in the traditional Chiense medicine （TCM） syndrome scores and gastric mucosa scores were observed before and after treatment. The Hamilton Anxiety Scale （HAMA） and Hamilton Depression Scale （HAMD） scores were also compared between the two groups before and after treatment. Results （1） During the study，1 patient was lost to follow-up in the observation group and 2 in the control group. Ultimately，39 cases in the observation group and 38 in the control group were included in the efficacy analysis.（2） The marked effectiveness rate was 79.49% （31/39） in the observation group and 13.16% （5/38） in the control group， with the observation group demonstrating significantly superior efficacy， the difference being statistically significant （P＜0.05）.（3） After treatment，both groups showed significant improvements in individual and total TCM syndrome scores （P＜0.05）， with the observation group exhibiting significantly greater improvements than the control group， the difference being statistically significant （P＜0.05）.（4） After treatment，both groups demonstrated significant improvements in gastric mucosa scores （P＜0.05）， with the observation group showing significantly superior improvement compared to the control group，the difference being statistically significant （P＜0.05）.（5） After treatment，both groups exhibited significant reductions in HAMA and HAMD scores （P＜0.05）， with the observation group achieving significantly greater reductions than the control group，the difference being statistically significant （P＜ 0.05）. Conclusion Acupoint catgut embedding combined with bloodletting pricking at Zhongwan point significantly alleviates clinical symptoms， reduces anxiety and depression， and improves gastric mucosal inflammation in patients with CNAG of liver-stomach disharmony type，demonstrating notable clinical efficacy.

R246.9

国家自然科学基金资助项目（编号：81473756）；中山市科学技术局科研项目（编号：2023B1132）