【目的】 分析老年衰弱患者静脉血栓栓塞症（VTE）与中医体质类型的相关性。【方法】 回顾性筛选广东省中医院综合二科 2019年1月至2023年6月收治的1 428例老年衰弱患者进行研究，依据患者静脉血栓发生情况分为静脉血栓组187例和非静 脉血栓组 1 241例。分析 2组患者的基线资料，对比 2组患者的年龄分布、Padua评分、Wells评分以及中医体质类型分布差 异，并采用多因素Logistic回归分析探讨老年衰弱患者VTE的影响因素。【结果】（1）与非静脉血栓组相比，静脉血栓组患者的 住院总费用、住院天数、年龄、Fried评分、Padua评分及Wells评分均显著升高，差异均有统计学意义（P＜0.001）。（2）与非 静脉血栓组相比，静脉血栓组的VTE高风险人群及Wells评分为2分的患者显著升高，差异均有统计学意义（P＜0.001）。（3）静脉 血栓患者60～69、70～79、80～89、90岁及以上年龄段的分布呈递增趋势，且其年龄分布与非静脉血栓组患者比较，差异 有统计学意义（P＜0.001）。（4）与非静脉血栓组比较，静脉血栓组患者的气虚质、血瘀质及气郁质占比更高（P＜0.05 或 P＜ 0.001）。（5）多因素Logistic回归分析结果（模型校正年龄、性别、衰弱及其他评分后）发现，老年衰弱静脉血栓患者中气虚质、 阳虚质为非易感体质，而湿热质、血瘀质、气郁质为易感体质（P＜0.05或 P＜0.01）。【结论】 老年衰弱患者静脉血栓栓塞症 与中医体质类型具有显著相关性，偏颇体质是老年衰弱患者的中医体质类型特征，湿热质、血瘀质、气郁质是老年衰弱患 者并发VTE的危险因素。

Objective To analyze the correlation between venous thromboembolism （VTE） and traditional Chinese medicine （TCM） constitution types in elderly frail patients. Methods A retrospective study was conducted on 1 428 elderly frail patients admitted to the Second Comprehensive Department of Guangdong Provincial Hospital of Chinese Medicine from January 2019 to June 2023. Patients were divided into a venous thrombsis （VT） group （n=187） and a non-VT group （n=1 241） based on VTE occurrence. Baseline data， including age distribution， Padua scores，Wells scores，and TCM constitution types，were compared between the two groups. Multivariate logistic regression analysis was performed to identify factors for influencing VTE in elderly frail patients. Results（1）Compared with the non-VT group，the VT group had significantly higher total hospitalization costs，length of stay，age， Fried scores，Padua scores，and Wells scores，with statistically significance （P＜0.001）.（2）Compared with the non-VT group， the VT group had a higher proportion of high VTE-risk individuals and those with Wells scores of 2 points， with statistically significance （P＜0.001）. （3） The age distribution of VTE patients showed an increasing trend in the age groups of 60-69，70-79，80-89，and ≥90-year-old，with a significant difference compared to the non-VT group （P＜0.001）.（4） The VT group had a higher proportion of qi-deficiency，bloodstasis，and qi-depression constitutions than the non-VT group （P＜0.05 or P＜0.001）.（5） Multivariate logistic regression analysis （after adjusting age，gender，frailty，and other scores） showed that qi-deficiency and yangdeficiency constitutions were non-susceptible，while damp-heat，blood-stasis，and qi-depression constitutions were susceptible to VTE in elderly frail patients （P＜0.05 or P＜0.01）. Conclusion VTE in elderly frail patients is significantly correlated with TCM constitution types. Deviated constitutions are characteristic of TCM constitution types in elderly frail patients，and damp-heat，blood-stasis，and qi-depression constitutions are risk factors for VTE in this population.

R259.92

广东省中医药局科研项目（编号：20232057）