【目的】 运用数据挖掘技术分析并总结针灸治疗黄褐斑的选穴规律。【方法】 计算机检索中国知网期刊全文数据库 （CNKI）、万方学术期刊全文数据库（Wanfang）、维普中文科技期刊数据库（VIP）、中国生物医学数据库（CBM）、美国生物医 学信息检索系统（PubMed）、荷兰医学文摘（Embase）、国际循证医学图书馆（Cochrane Library）等各大数据库。检索 2003 年 1 月1日至 2024 年8月31日收录的针灸治疗黄褐斑的临床研究文献，利用 Microsoft Excel 2019建立针灸治疗黄褐斑数据库， 采用 SPSS Modeler 18.0 、Cytoscape 3.9.1 和 SPSS 26.0 对腧穴进行使用频次、归经、分布、特定穴分析，以及关联规则分析、 聚类分析。【结果】 共纳入文献 122 篇，涉及针灸处方 185 个、腧穴 131 个，总应用频次为 1 532次。高频腧穴为三阴交、足 三里、血海、合谷等；常用经脉为足太阴脾经、足阳明胃经、任脉、足太阳膀胱经和手阳明大肠经；特定穴多为募穴、五 输穴、下合穴；腧穴多分布于胸腹部和下肢部。关联规则分析显示，核心穴组为“三阴交-足三里-血海-合谷”。聚类分析 将高频腧穴分为 5大类。【结论】 针灸治疗黄褐斑的选穴规律体现了整体观念与辨证论治相结合的原则，核心穴组为“三阴 交-足三里-血海-合谷”，治疗时多选用胸腹部、下肢部穴位，并结合头面部穴位。

Objective To analyze and summarize the acupoint selection patterns for acupuncture-moxibustion treatment of chloasma using data mining techniques. Methods Computerized searches were conducted in major databases including the CNKI，Wanfang，VIP，CBM，PubMed，Embase，and the Cochrane Library. Clinical research literature on acupuncture-moxibustion treatment of chloasma published between January 1， 2003 and August 31，2024 was retrieved. A database for acupuncture-moxibustion treatment of chloasma was established using Microsoft Excel 2019，and SPSS Modeler 18.0，Cytoscape 3.9.1，and SPSS 26.0 were employed to analyze the frequency of acupoint usage，meridian tropism，regional distribution，and specific acupoint categories，as well as to perform association rule analysis and cluster analysis. Results A total of 122 articles were included， involving 185 acupuncture-moxibustion prescriptions and 131 acupoints，with a total application frequency of 1 532. High-frequency acupoints included Sanyinjiao（SP6）， Zusanli（ST36）， Xuehai（SP10）， and Hegu （LI4）. Commonly used meridians were the spleen meridian of foot-taiyin， stomach meridian of foot-yangming， conception vessel （ren mai），bladder meridian of foot-taiyang，and large intestine meridian of hand-yangming. Specific acupoints were predominantly front-mu points，five-shu points，and lower he-sea points. Acupoints were mostly distributed in the chest/abdomen and lower limbs. Association rule analysis revealed that the core acupoint combination was “Sanyinjiao-Zusanli-Xuehai-Hegu”. Cluster analysis classified high-frequency acupoints into five major categories. Conclusion The acupoint selection patterns for acupuncture-moxibustion treatment of chloasma reflect the principle of combining holistic concepts with syndrome differentiation. The core acupoint combination is “Sanyinjiao-Zusanli-Xuehai-Hegu”. During treatment，acupoints in the chest/abdomen and lower limbs are frequently selected，often combined with acupoints on the head and face.

R246.9

国家自然科学基金项目（编号：82474617）；安徽省研究生质量工程项目特色学位点建设资助项目（编号：2022tsxwd040）