鲜药是区别于干药的中医治疗手段之一，在皮肤科中应用广泛，可用于治疗单纯疱疹、带状疱疹、寻常疣、扁平疣、 疖、痈、丹毒、寻常痤疮、真菌性皮肤病、银屑病、接触性皮炎、虫咬皮炎、湿疹等皮肤疾病。常用于治疗皮肤病的鲜药 有鲜马齿苋、鲜鱼腥草、鲜茜草、鲜海金沙、鲜败酱草、鲜芦荟、鲜车前草、鲜半夏、鲜蒲公英等，此类药物多具有清热 解毒凉血的作用。鲜药治疗皮肤疾病可采用内服或外用，但以外用或内服与外用联合运用为主。由于现代社会的快速发展， 鲜药的供应及标准无法跟上庞大的病患群体需求而逐渐淡出视野，但鲜药的作用不可被干药替代。该文通过综述中药鲜药 在皮肤科的现代应用进展，以期促进鲜药治疗皮肤科疾病的相关研究及扩大其临床应用。

Fresh Chinese herbal medicine， being distinct from the dried herbs， is one of the therapies of traditional Chinese medicine（TCM） widely used in dermatology. It is employed to treat various skin diseases， namely herpes simplex，herpes zoster，common warts，flat warts，boils，carbuncles，erysipelas，acne vulgaris， fungal skin diseases，psoriasis，contact dermatitis，insect bite dermatitis，and eczema. The commonly-used fresh herbs for skin diseases are fresh Portulacae Herba，fresh Houttuyniae Herba，fresh Rubiae Radix，fresh Lygodii Spora，fresh Patriniae Herba，fresh Aloe，fresh Plataginis Herba，fresh Pinelliae Rhizoma，and fresh Taraxaci Herba. These herbs usually have the actions of clearing heat，detoxifying，and cooling blood. For the treatment of skin diseases，fresh herbal medicine can be administered orally or applied topically，with a predominant use of topical application or a combination of oral and topical administration. Due to the rapid development of modern society， the supply and standardization of fresh herbs fail in meeting the demands of a large population of the patients，leading to their gradual decline in use. However，the efficacy of fresh herbs cannot be entirely replaced by that of the dried herbs. This article reviewed the advances in the modern application of fresh Chinese herbal medicine in dermatology，aiming to promote further research and expand its clinical application in treating skin diseases.

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广东省中医药局中医药科研项目（编号：20231293，20241268）；深圳市“医疗卫生三名工程”项目（编号：SZZYSM202106008）； 深圳市宝安区医疗卫生基础研究项目（编号：2020JD510）