免疫性血小板减少症（ITP）是一种免疫介导的出血性疾病，可归属于中医的“紫癜病”范畴。现代中医认为，ITP 为 本虚标实之证，多从热、虚、瘀辨治。邓聪教授提出，ITP的发生是内外因相互作用的结果，风邪侵袭为外因，情志失常、 日久劳倦是其内因；致病因素以风、虚、瘀为主；病机为风引伏风，肝不藏血，脾不统血，肾不生血，血溢脉外，病位在 肝、脾、肾。风邪内动、肝不藏血、脾不统血和肾不生血是导致ITP难以痊愈的重要因素，辨证施治ITP需厘清肝、脾、肾 的功能特点及其相互影响的机制，以祛风柔肝、化瘀健脾、补肾填精为法，重视运用风药、柔肝之药和血肉有情之品。邓 聪教授从风、虚、瘀辨治ITP，为ITP患者提供了更多的治疗选择，尤其是对于慢性及难治性血小板减少性紫癜的患者。

Immunologic thrombocytopenic purpura（ITP） is an immune-mediated hemorrhagic disorder that can be categorized as purpura disease in traditional Chinese medicine（TCM）. Modern TCM views ITP as a syndrome being deficiency in the origin and excess in the superficiality，and the treatment of ITP is usually from the pathogenesis of heat，deficiency，and stasis. Professor Deng Cong proposes that the onset of ITP results from the interaction of internal etiological factors and external etiological factors， the invasion of wind acting as the exogenous cause， while emotional disturbances and chronic fatigue serving as endogenous contributors. The primary pathogenic factors are wind，deficiency，and stasis. The onset of ITP is due to wind stirring latent pathogens，liver failing to store blood，spleen failing to govern blood，and kidney failing to generate blood，which cause the extravasation of blood from the vessels. ITP primarily involves the liver，spleen and kidney. Internal stirring of wind pathogen， liver failing to store blood，spleen failing to govern blood，and kidney failing to generate blood are the critical factors contributing to the refractory ITP. Syndrome differentiation and treatment of ITP requires the identification of the functional characteristics of the liver， spleen， and kidneys as well as their interrelationships. Therapeutic strategies should focus on dispelling wind and soothing the liver，resolving stasis and strengthening the spleen， and tonifying the kidneys to supplement essence， with emphasis on using wind-dispelling medicinals， liversoothing medicinals，and medicinal with affinity to flesh and blood. Professor Deng Cong’s approach to treating ITP from the pathogenesis of wind，deficiency and stasis will provide an additional option for the treatment of ITP， particularly for the patients with chronic and refractory thrombocytopenic purpura.

R259.582

广东省临床教学基地教学改革研究项目（编号：2019JD029）；广东省教育厅临床教改项目（粤教高函 〔2023〕 32号：178）