[关键词]
[摘要]
Burkitt淋巴瘤属于非霍奇金淋巴瘤中的一种,其病位不固定,病情变化快,症状繁多,临床辨治较复杂。王晞星教授 认为,Burkitt淋巴瘤是有形之体,其形成与外邪侵袭、七情内伤、正气内虚等有关,其病机以肝脾肾三脏功能失调为本,致 使肝郁气滞、中焦脾胃虚弱、肝肾不调;以痰湿毒瘀互结为标,本虚标实,虚实夹杂。临证治疗时,将辨病与辨证相结合, 注重调和肝脾肾三脏,维持机体阴阳平衡。治疗从疏肝理气、益气健脾、补肾调肝等入手,分别采用柴胡散结汤、补中益 气汤、补肾调肝汤等方药,疗效较显著。
[Key word]
[Abstract]
As a type of non-Hodgkin lymphoma, Burkitt lymphoma is characterized by unfixed location of disease, rapid progression, diverse symptoms, and clinical complexity in diagnosis and treatment. Professor Wang Xixing posits that Burkitt lymphoma manifests as a tangible mass,and its formation is associated with the invasion of exogenous pathogens,internal injury induced by seven emotions,and deficiency of healthy qi. The fundamental pathogenesis involves dysfunction of the liver, spleen and kidney, leading to liver qi stagnation, spleen-stomach deficiency in the middle energizer,and liver-kidney disharmony. The secondary manifestations were caused by the binding of phlegm-damp,toxin,and stasis. In general,the pathogenesis of Burkitt lymphoma presented deficiency in the origin and excess in the superficiality, and deficiency interweaved with excess. In clinical practice, Professor Wang emphasizes the regulation of the functions of liver, spleen and kidney, and maintains the body’s yin-yang balance on the basis of the combination of disease differentiation and syndrome differentiation. Therapeutic strategies focus on soothing liver qi, replenishing qi to strengthen the spleen, and tonifying the kidney to regulate the liver,separately through the utilization of Chaihu Sanjie Decoction,Buzhong Yiqi Decoction,and Bushen Tiaogan Decoction. In this way,significant clinical efficacy is usually achieved.
[中图分类号]
R273.34
[基金项目]
第四届国医大师传承工作室建设项目(国中医药办人教函 〔2022〕 245 号 1123-04);国家中医药传承创新中心建设项目(编号: 202203);山西省中医临床医学研究中心(培育)项目(晋科社发 〔2019〕 61 号);山西省卫健委医学科技创新团队项目(编号:2020TD04); 山西省卫健委医学重大科技攻关专项(编号:2022XM10)