广东省名中医刘凤斌教授擅长运用中药治疗肝胆、脾胃等消化系统疾病，对乙型病毒性肝炎（简称“乙肝”）及乙肝相 关肝纤维化的中药干预颇有心得。刘凤斌教授认为，湿、热、瘀、毒、虚是乙肝肝纤维化的主要致病因素；乙肝肝纤维化 的病位在肝，与脾、肾密切相关，并涉及胆、胃、三焦等。刘教授基于中医辨证思维，通过多年的临床实践，总结针对中 药干预乙肝肝纤维化的“治肝八法”，即健运脾胃法、清热祛湿法、祛湿化浊法、滋阴降火法、温阳补肾法、柔肝养血法、 活血软坚法、安神助眠法。临证时，依据患者证型和临床表现的不同，以此八法组合运用，并擅用具有岭南用药特色的药 物组合（简称“药组”），如清热解毒、利湿退黄药组（白背叶根、鸡骨草、叶下珠），消食化积药组（红曲、山楂、麦芽），破 血消积药组（醋莪术、醋鳖甲、土鳖虫），保肝降酶药组（枳椇子、五味子）。刘凤斌教授运用中药干预乙肝肝纤维化的用药 经验可为中医临床治疗肝病提供参考。

Professor Liu Fengbin，a renowned traditional Chinese medicine（TCM） expert in Guangdong Province， specializes in treating digestive system disorders of hepatobiliary and splenic diseases with Chinese herbal medicine，and has accumulated extensive experience in intervening viral hepatitis type B and hepatitis B-related liver fibrosis. Professor Liu proposes that dampness， heat， stasis， toxin， and deficiency are the primary pathogenic factors of hepatitis B-related liver fibrosis. The disease is rooted in the liver，and is also closely related to the spleen and kidney and involves the gallbladder，stomach，and triple energizer. Based on TCM dialectical thinking and years of clinical practice，Professor Liu summarized the “eight methods for treating liver diseases” for intervening hepatitis B-related liver fibrosis with Chinese medicine，i.e.，method of activating the spleen and stomach， method of clearing heat and dispelling dampness， method of dispelling dampness and resolving turbidity，method of enriching yin and subduing fire，method of warming yang and tonifying the kidney，method of softening the liver and nourishing blood，method of activating blood circulation and softening hardness，and method of calming the mind and improving sleep. In clinical practice，these methods are flexibly combined based on patients’ syndrome types and manifestations. Moreover，Professor Liu is skilled in using herbal groups having Lingnan medicinal characteristics， such as herbal group for clearing heat and removing toxin， and draining dampness to relieve jaundice which is composed of Mallotus Apelta Radix et Rhizoma，Abri Herba and Phyllanthi Urinariae Herba，herbal group for promoting digestion to remove food retention which is composed of Fermentum Rubrum，Crataegi Fructus and Hordei Fructus Germinatus，herbal group for removing blood and eliminating mass group which is composed of vinegar-processed Curcumae Rhizoma， vinegar-processed Trionycis Carapax and Eupolyphaga Steleophaga， and herbal group for protecting liver and lowering enzyme which is composed of Hoveniae Semen and Schisandrae Chinensis Fructus. Professor Liu’s medication experience for intervening hepatitis B-related liver fibrosis will provide valuable references for TCM clinical practice in the management of liver diseases.

R256.42

国家自然科学青年科学基金项目（编号：82104549）；中国博士后科学基金面上项目（编号：2020M672603）；广东省中医药局科研 项目（编号：20221145）；广东省中医药重点学科建设项目-肝病科（编号：08002011007）