国医大师林毅在总结历代医家的郁证学说精华的基础上，结合其自身丰富的临床经验，提出“六郁治乳”理论。其 认为乳腺疾病的发生与六郁有关，治疗应从六郁而治，即从气郁、血郁、痰郁、湿郁、食郁、火郁入手辨治乳腺病。乳腺 癌的发生、发展与内环境失衡、六郁内生密切相关，是中医辨证论治的重点病种之一。国医大师林毅提出，早期乳腺癌应 进行分期辨证治疗，即分为围手术期、围化疗期、围放疗期及巩固期4期进行分型，结合“六郁治乳”理论，采用疏肝、化 痰、祛瘀、清热、利湿、消食、健脾、补肾等治法，以达到调和内环境、改善症状的目的。“六郁治乳”理论丰富了中医防 治乳腺癌的理论体系，使早期乳腺癌分期辨证的治疗原则和理法方药趋于完善，对提高中西医结合治疗早期乳腺癌的疗效 具有重要意义。

By aggregating the essence of theories related with depressive syndrome from historical medical practitioners and based on the extensive clinical experience，traditional Chinese medicine （TCM） master Lin Yi proposed the theory of six-stagnation-based breast disease prevention and treatment. She pointed out that the occurrence of breast diseases is related to six stagnations （qi stagnancy， blood stagnancy， phlegm stagnancy， dampness stagnancy，food stagnancy，and fire stagnancy），and the treatment for breast diseases should start from the six stagnations. The development and progression of breast cancer is closely associated with the imbalance of internal environment and the formation of six stagnations，and breast cancer is one of the major diseases suitable for the TCM syndrome differentiation and treatment. For the treatment of early breast cancer， Professor Lin Yi proposed to divide early breast cancer into four stages，namely perioperative period，peri-chemotherapy period， peri-radiotherapy period，and consolidation period. Guided by the theory of six-stagnation-based breast disease prevention and treatment， therapies of soothing the liver， resolving phlegm， removing stasis， clearing heat， eliminating dampness， promoting digestion， fortifying the spleen， and tonifying the kidney are employed to harmonize the internal environment and alleviate symptoms. The theory of six-stagnation-based breast disease prevention and treatment enriches the TCM theory for the prevention and treatment of breast cancer，refines the principles and methods for the staging and syndrome differentiation of early breast cancer，and holds significant implications for enhancing the efficacy of integrated TCM and western medicine in managing early breast cancer.

R273.79

国家中医药管理局第七批全国老中医药专家学术经验继承工作项目（编号：0102016402）