【目的】基于运气学说分析原发性闭角型青光眼 （PACG） 患者禀赋特点，为揭示PACG的病因病机及发病规律提供思路。 【方法】纳入2023年10月至2024年3月就诊于中国中医科学院眼科医院的PACG患者204例，以出生日期推算受孕日期，将 其受孕日期转化为干支纪年后推算五运六气，录入数据库，统计分析其受孕禀赋特征。【结果】PACG患者受孕日期的主气、 客气、司天在泉分布差异无统计学意义 （P > 0.05） ，而岁运、综合运气、运气相合分布差异有统计学意义 （P < 0.05） ，且受孕 禀赋为少木-阳明燥金-少阴君火、太土-少阴君火-阳明燥金的PACG患者人数最多。【结论】受孕禀赋为少木、太土，综合运 气为少木-阳明燥金-少阴君火、太土-少阴君火-阳明燥金，运气相合为顺化年、天刑年者更易罹患PACG，故推测PACG患 者的体质可能与燥邪袭肺，金胜乘木有关。

Objective To analyze the endowment features of patients with primary angle-closure glaucoma（PACG） based on circuit-qi theory，thus to provide approaches for revealing the etiology，pathogenesis and prevalence of PACG. Methods From October 2023 to March 2024， a total of 204 patients with PACG admitted to the Eye Hospital， China Academy of Chinese Medical Sciences were enrolled into the analysis. The natal day of the patients was used for the calculation of conception day，and then the conception day was used for the analysis of the features of five circuits and six qi based on the stem-branch lunar year of conception day. A database of information of five circuits and sixqi on conception day was constructed，and then the features of their endowments at conception were statistically analyzed. Results No statistically significant differences were shown in the distribution of the dominantqi ，guestqi ，sitian （celestial control）andzaiquan （terrestrial effect）at conception in PACG patients（P > 0.05），but there were statistically significant differences in the distribution of yearly circuit， comprehensive circuit-qi ， and combined circuit-qi at conception in PACG patients（P < 0.05）. Most of PACG patients had the circuit-qi features ofshaomu（deficiency of wood）-yangming dryness gold-shaoyin monarch fire， andtaitu （excess of earth）-shaoyin monarch fire-yangming dryness gold at conception. Conclusion Those who are conceived at the date with circuit-qi features ofshaomu andtaitu ，comprehensive circuit-qi features ofshaomu - yangming dryness gold-shaoyin monarch fire and taitu -shaoyin monarch fire-yangming dryness gold， and combined circuit-qi features ofshunhua （qi generating circuit）and celestial restriction（qi restricting circuit）are vulnerability to PACG. The development of the constitution of PACG patients may be related to the congenital circuit-qi features of pathogenic dryness attacking the lung，and metal exuberance restricting wood.

R276.7

国家重点研发计划项目 （编号：2022YFC3502501） ；国家自然科学基金面上项目 （编号：82074500）； 中国中医科学院眼科医院中 央高水平中医医院项目 （编号：GSP3-15， GSP5-77）