【目的】 观察炙甘草汤加减联合针刺治疗气阴两虚型室性心律失常的临床疗效。【方法】 选取 2023年 1月至 2024年 1月 期间于齐齐哈尔市中医医院病房及门诊收治的气阴两虚型室性心律失常患者60例，按随机数字表法将患者随机分为观察组 和对照组，每组各30例。对照组给予盐酸美西律片治疗，观察组在对照组治疗的基础上，给予炙甘草汤加减联合针刺治疗， 连续治疗2周。治疗2周后，评价2组中医证候疗效及Lown分级疗效，观察2组患者治疗前后室性早搏次数及占总心搏比的 变化情况，以及中医证候积分的情况。比较2组患者治疗前后QT间期及Tp-ec间期的变化情况。【结果】（1）治疗后，2组患 者的室性早搏次数及占总心搏比均明显改善（P < 0.05），且观察组在改善室性早搏次数及占总心搏比方面明显优于对照组， 差异有统计学意义（P < 0.05）。（2）治疗后，2组患者的中医证候积分明显改善（P < 0.05），且观察组在改善中医证候积分方面 明显优于对照组，差异有统计学意义（P < 0.05）。（3）观察组中医证候疗效总有效率为 90.00%（27/30），对照组为 60.00% （18/30）。观察组疗效优于对照组，差异有统计学意义（P < 0.05）。（4）观察组Lown分级疗效总有效率为93.33%（28/30），对照 组为76.67%（23/30）。观察组疗效优于对照组，差异有统计学意义（P < 0.05）。（5）治疗后，2组患者的QT间期与Tp-ec间期明 显改善（P < 0.05），且观察组在改善 QT间期与 Tp-ec间期方面明显优于对照组，差异有统计学意义（P < 0.05）。【结论】 炙甘 草汤加减联合针刺治疗气阴两虚型室性心律失常，能明显改善患者的临床症状，疗效显著。

Objective To observe the clinical efficacy of modified Zhi Gancao Decoction combined with acupuncture in the treatment of ventricular arrhythmia with qi and yin deficiency type. Methods Sixty patients with ventricular arrhythmia of qi and yin deficiency type admitted to the wards and outpatient clinics of Hospital of Traditional Chinese Medicine of Qiqihar between January 2023 and January 2024 were selected，and the patients were randomly divided into the observation group and the control group according to the random number table method，with 30 patients in each group. The control group was treated with Mexiletine Hydrochloride Tablets，and the observation group was treated with modified Zhi Gancao Decoction combined with acupuncture on the basis of the treatment of the control group， the course of treatment covered two consecutive weeks. After two weeks of treatment， the efficacy of traditional Chinese medicine （TCM） syndrome and Lown grading were evaluated between the two groups，the changes of the number of ventricular premature beats，the total beat ratio，and TCM syndrome scores before and after treatment in the two groups were observed. The changes of QT interval and Tp-ecinterval before and after treatment were compared between the two groups. Results（1）After treatment， the number of premature ventricular beats and the total beat ratio of the two groups were improved significantly（P < 0.05），and the improvement in the observation group was significantly superior to that in the control group，the difference being statistically significant（P < 0.05）.（2）After treatment，the TCM syndrome scores of patients in the two groups were improved significantly（P < 0.05）， and the improvement in the observation group was significantly superior to that in the control group，the difference being statistically significant（P < 0.05）.（3）The total effective rate of TCM syndrome in the observation group was 90.00%（27/30），and 60.00%（18/30）in the control group. The efficacy of the observation group was superior to that of the control group，the difference being statistically significant（P < 0.05）.（4）The total effective rate of Lown grading efficacy was 93.33%（28/30）in the observation group and 76.67%（23/30）in the control group. The efficacy of the observation group was superior to that of the control group， the difference being statistically significant（P < 0.05）.（5）After treatment， the QT interval and Tp-ec interval of patients in the two groups were improved significantly（P < 0.05）， and the improvement in the observation group was significantly superior to that in the control group，with a statistically significant difference（P < 0.05）. Conclusion Modified Zhi Gancao Decoction combined with acupuncture in the treatment of ventricular arrhythmia with qi and yin deficiency type can significantly improve the clinical symptoms of the patients.

R246.9

国家自然科学基金青年科学基金资助项目（编号：82104962）；黑龙江省青年人才托举工程项目资助项目（编号：2022-QNRC1-28）； 齐齐哈尔市科技攻关资助项目（编号：CSFGG-2023161，CSFGG-2023181）