阻塞性睡眠呼吸暂停低通气综合征 （OSAHS） 是一种常见的睡眠呼吸障碍性疾患，易引起多器官、多系统损害；可归属中医学的“鼾证”。全国名中医张忠德教授以平调五脏法辨治阻塞性睡眠呼吸暂停低通气综合征，强调五脏“失衡”的发病机理；认为肺气失于宣降是OSAHS的发病之基础；“脾胃失于运化，痰湿内生”是OSAHS的关键致病因素，“心肾之阳虚，肝血之不足”是OSAHS的发病之根本。发病过程中五脏之间阴阳气血此消彼长，从而导致疾病的发展。辨证治疗以“平”为度，通过“平调”的思维，以“健脾、宣肺、温心肾、养肝血”为治则，五脏同调，从而达到各脏器间的动态平衡，起到治疗疾病的目的。

Obstructive sleep apnea hypopnea syndrome （OSAHS） is the common sleep-related breathing disorders，which is prone to develop into multi-organ and multi-system damages. OSAHS can be categorized as “snoring syndrome” in traditional Chinese medicine（TCM） . Professor ZHANG Zhong-De，a national famous Chinese medical practitioner，advocates to treat OSAHS with the method of uniform regulation of five zang organs，and emphasizes the importance of pathogenesis of imbalance of the five zang-organs. In his view，failure of lung qi in dispersing and descending is the basic pathogenesis of OSAHS，spleen and stomach failing in transporting and transforming as well as internal retention of phlegm-damp is the key pathogenic factors of OSAHS，and heart-kidney yang deficiency and liver blood insufficiency contribute to the fundamental pathogenesis of OSAHS. In the course of OSAHS，the yin and yang，qi and blood of the five zang organs become imbalanced，which leads to the progression of the disease. The treatment based on syndrome differentiation for OSAHS aims at restoring the state of balance. Following the principle of uniform regulation，methods of invigorating spleen，ventilating lung，warming heart and kidney，and nourishing liver blood are used for the uniform regulation of five zang organs，so as to keep the dynamic balance among the organs and to cure the disease.

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广东省科技厅项目 （编号：2020A1414040032）；广州市科技局市校联合项目 （编号：202201020498）；第二届全国名中医传承工作室建设项目 （粤中医办函[2022]52号）；广东省中医院中医药科学技术研究专项 （编号：YN2018QL09，YN2020QN25）