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[摘要]
【目的】观察秩边透水道针刺法治疗脊髓损伤 (SCI) 后神经源性膀胱 (NB) 的临床疗效。 【方法】将120例SCI后NB患者随机分为观察组和对照组,每组各60例。对照组给予常规药物治疗及健康宣教,观察组在对照组治疗的基础上,给予秩边透水道针刺治疗。2组均治疗30 d。治疗1个月后,评价2组临床疗效,观察2组患者治疗前后膀胱残余尿量和最大容量、最大排尿量及每日排尿次数的变化情况,以及患者排尿末期时的逼尿肌压力的情况。比较2组患者治疗前后简易版神经源性膀胱患者生活质量测评量表 (SF-Qualiveen) 评分的变化情况。并评价2组的安全性及不良反应的发生情况。 【结果】(1) 观察组总有效率为86.67% (52/60) ,对照组为65.00% (39/60) 。观察组疗效优于对照组,差异有统计学意义 (P<0.05) 。 (2) 治疗后,2组患者的膀胱残余尿量、膀胱最大容量、最大排尿量、每日排尿次数均明显改善 (P<0.05) ,且观察组在改善膀胱残余尿量、膀胱最大容量、最大排尿量、每日排尿次数方面明显优于对照组,差异均有统计学意义 (P<0.05) 。 (3) 治疗后,2组患者的排尿末期逼尿肌压力明显改善 (P<0.05) ,且观察组在改善排尿末期逼尿肌压力方面明显优于对照组,差异有统计学意义 (P<0.05) 。 (4) 治疗后,2组患者的SF-Qualiveen评分明显改善 (P<0.05) ,且观察组在改善SF-Qualiveen评分方面明显优于对照组,差异有统计学意义 (P<0.05) 。 (5) 2组患者的不良反应发生率比较,差异无统计学意义 (P>0.05) 。 【结论】秩边透水道针刺法治疗SCI后NB,能明显改善患者的临床症状,有效改善患者的膀胱功能,提高患者逼尿肌压力,从而提高患者的生活质量,疗效显著。
[Key word]
[Abstract]
Objective To observe the clinical efficacy of the Zhibian(BL54)-through-Shuidao(ST28) insertion acupuncture method for the treatment of neurogenic bladder (NB) after spinal cord injury (SCI) . Methods A total of 120 patients with NB after SCI were randomly divided into observation group and control group,60 patients in each group, the control group was given conventional medicinal treatment and health education, and the observation group was given Zhibian-through-Shuidao insertion acupuncture for treatment on the basis of the control group. Both groups were treated for 30 days. After one month of treatment,the clinical efficacy of the two groups was evaluated,and changes in the bladder residual urine volume and maximal urination volume,maximum voided volume and daily voiding frequency,as well as the detrusor pressure at the end of urination of patients in the two groups were observed. The changes of Short-Form Health Survey-Qualiveen (SF-Qualiveen) scores before and after treatment were compared between the two groups of patients. And the safety and the occurrence of adverse reactions in the two groups was evaluated. Results (1) The total effective rate was 86.67%(52/60) in the observation group and 65.00% (39/60) in the control group. The efficacy of the observation group was superior tothat of the control group,and the difference was statistically significant(P<0.05) . (2)After treatment,the bladder residual urine volume,maximal urination volume,maximum voided volume,and daily voiding frequency of the patients in the two groups were significantly improved(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,and the difference was statistically significant(P<0.05) . (3)After treatment,the detrusor pressure at the end of urination of the two groups of patients were significantly improved (P<0.05) ,and the improvement in the observation group was significantly superior to that in the control group,and the difference was statistically significant (P<0.05) . (4) After treatment,the SF-Qualiveen scores of the two groups of patients were improved significantly (P<0.05) ,and the improvement in the observation group was significantly superior to that in the control group, and the difference was statistically significant(P<0.05) . (5)Comparison of the incidence of adverse reactions between the two groups of patients,the difference was not statistically significant (P>0.05) . Conclusion The treatment of NB after SCI with Zhibian-through-Shuidao insertion acupuncture method can significantly improve the clinical symptoms of the patients,effectively improve the bladder function of the patients,and increase the detrusor pressure of patients,so as to enhance the quality of life of the patients,and the therapeutic efficacy is remarkable.
[中图分类号]
R246.9
[基金项目]
湖北省教育厅科学研究计划指导性项目 (编号:B2021206);潜江市公益性行业科研计划资助项目 (编号:2023GYX011)