【目的】观察基于五运六气理论，癸卯年运用审平汤加味治疗燥热伤肺型儿童过敏性鼻炎 （AR） 的临床疗效。 【方法】将60例燥热伤肺型AR患儿随机分为治疗组和对照组，每组各30例。对照组给予口服盐酸西替利嗪滴剂治疗，治疗组给予审平汤加味联合盐酸西替利嗪滴剂治疗，疗程为2周。观察2组患儿治疗前后中医证候积分、儿童过敏性鼻炎生活质量测评量表评分、症状严重程度视觉模拟量表 （VAS） 评分的变化情况，并评估2组患儿的中医证候疗效。 【结果】（1） 疗效方面：治疗2周后，治疗组的总有效率为93.33% （28/30） ，对照组为70.00% （21/30） ，组间比较，治疗组的中医证候疗效明显优于对照组（P＜0.05） 。 （2） 中医证候积分方面：治疗后，2组患儿的中医证候积分均较治疗前明显降低 （P＜0.01） ，且治疗组的降低幅度明显优于对照组 （P＜0.05） 。 （3） 生活质量评分方面：治疗后，2组患儿的儿童过敏性鼻炎生活质量测评量表评分均较治疗前明显降低 （P＜0.01） ，且治疗组的降低幅度明显优于对照组 （P＜0.01） 。 （4） 症状严重程度VAS评分方面：治疗后，2组患儿的症状严重程度 （包括喷嚏、鼻塞、流涕、鼻痒4项症状） VAS评分均较治疗前明显降低 （P＜0.01） ，且治疗组的降低幅度明显优于对照组 （P＜0.01） 。 【结论】癸卯年运用审平汤加味联合盐酸西替利嗪滴剂治疗燥热伤肺型AR患儿疗效显著，较单纯口服盐酸西替利嗪滴剂在改善患儿临床症状、提高患儿生活质量方面更具有优势。

Objective To observe the clinical efficacy of modified Shenping Decoction in the treatment of allergic rhinitis （AR） in children in Gui-Mao year，a stem-branch Chinese lunar year，based on the theory of five-circuit and six-qi theory. Methods Sixty children with AR of dryness-heat impairing lung type were randomly divided into the treatment group and the control group，with 30 cases in each group. The control group was treated with Cetirizine Hydrochloride Drops orally，and the treatment group was treated with modified Shenping Decoction combined with Cetirizine Hydrochloride Drops. The course of treatment for the two groups covered two weeks. The changes in the scores of traditional Chinese medicine （TCM） syndrome，quality of life （QOL） rating scale，and visual analogue scale （VAS） for AR symptoms in the two groups before and after treatment were observed. After treatment，the efficacy for TCM syndrome in the two groups were evaluated. Results （1） After two weeks of treatment，the total effective rate of the treatment group was 93.33% （28/30） ，and that of the control group was 70.00% （21/30）；the intergroup comparison showed that the TCM syndrome efficacy in the treatment group was significantly superior to that in the control group （P＜0.05） . （2） After treatment，the TCM syndrome scores in the two groups were significantly decreased when compared with those before treatment （P＜0.01） ，and the decrease in the treatment group was significantly superior to that in the control group （P＜0.05） . （3） After treatment，the QOL rating scale scores of children with AR in both groups were significantly decreased when compared with those before treatment （P＜0.01） ，and the decrease in the treatment group was significantly superior to that in the control group （P＜0.01） . （4） After treatment， the VAS scores for severity of symptoms （including four symptoms，namely sneezing，stuffy nose，runny nose，and itchy nose） in the two groups were significantly decreased when compared with those before treatment（P＜0.01）， and the decrease in the treatment group was significantly superior to that in the control group（P＜0.01） . Conclusion In Gui-Mao year， the application of Shenping Decoction combined with Cetirizine Hydrochloride Drops in the treatment of AR children dryness-heat impairing lung type can achieve significant clinical efficacy. The combined use has more advantageous than oral use of Cetirizine Hydrochloride Drops alone in improving the clinical symptoms and quality of life of the AR children.

R276.1

广东省中医药局科研项目 （编号：20241279）