【目的】探究中年人糖尿病罹患的运气禀赋与高风险因素的相关性。 【方法】分析深圳市广州中医药大学深圳医院 （福田） 中年糖尿病患者611例，根据出生日期推算患者所属运气情况以及运气相合情况，采用卡方检验和Logistic回归分析影响罹患因素。 【结果】（1） 岁运分布为火运太过 （太火） 最多，差异有统计学意义 （χ2= 24.794，P = 0.003） 。 （2） 主运为金运分布最多，客运为水运不及 （少水） 分布最多，差异均有统计学意义 （χ2= 10.678，P = 0.030；χ2= 18.411，P = 0.031） 。 （3） 主气分布为太阴湿土最多，客气分布为少阴君火最多，差异均有统计学意义 （χ2= 15.268，P = 0.009；χ2= 11.282，P = 0.046） 。 （4） 运气相合情况最多为异化小逆年，差异有统计学意义 （χ2= 236.28，P＜0.001） 。 （5） 男性患者中出生时间的主气为太阴湿土时段罹患糖尿病风险高于女性，差异有统计学意义 （OR = 0.554，95%置信区间为0.321～0.955，P = 0.034） 。 【结论】患有糖尿病的中年人出生日期存在岁运为太火、主运为金运、客运为少水、主气为太阴湿土、客气为少阴君火、运气相合年份为小逆年的五运六气特征，提示中年人罹患糖尿病与先天运气禀赋相关，应重点注意火、寒、湿三种因素的影响。

Objective To investigate the correlation between the prevalence of diabetes mellitus （SM） in middle-aged people and the circuit-qi endowment，and to explore the high-risk circuit-qi factors for DM. Methods A total of 611 middle-aged DM patients from Shenzhen Futian Hospital of Guangzhou University of Chinese Medicine were included for the analysis. The features of five circuits and six qi as well as the combined circuit-qi features on the birth date of the patients were analyzed and then the influencing factors of DM prevalence were explored by chi-square test and Logistic regression analysis. Results （1） The distribution of the yearly circuit in the middle-aged DM patients showed that the excessive fire circuit （taihuo） accounted for the most， and the difference was statistically significant（χ2= 24.794，P = 0.003） . （2） The dominant circuit of the middle-aged DM patients was predominated by gold circuit and the guest circuit was predominated by deficiency water circuit （shaoshui），and the difference was all statistically significant（χ2= 10.678，P = 0.030；χ2= 18.411，P = 0.031） . （3）The predominant qi of the middle-aged DM patients was predominated by taiyin wet-earth and the guest qi was predominated by shaoyin monarch-fire，all with statistically significant differences （χ2 = 15.268，P = 0.009；χ2= 11.282，P = 0.046） . （4） The distribution of the circuit-qi combination showed that mildly-rebellious year （the year of circuit generating qi） accounted for the most，and the difference was statistically significant （χ2= 236.28，P＜0.001） . （5） For the people born in the period with the dominant qi being taiyin wet-earth，the male had higher risk of suffering from DM than the female，and the difference was statistically significant （OR = 0.554，95% confidence interval being 0.321-0.955，P = 0.034） . Conclusion The middle-aged people suffering from DM have the following five-circuit and six-qi features： the yearly circuit being predominated by excessive fire circuit （taihuo），the dominant circuit being predominated by gold circuit，the guest circuit being predominated by deficiency water circuit （shaoshui），the predominant qi being predominated by taiyin wet-earth，the guest qi being predominated by shaoyin monarch-fire，and the circuit-qi combination being predominated by mildly-rebellious year. The results indicated that the prevalence of DM in the middle-aged people is related to the congenital circuit-qi endowment，and the impacts of the factors of fire，cold，and dampness should be taken into account.

R259.871

国家自然科学基金资助项目 （编号：82374380）；深圳市科技创新委员会科技计划项目 （编号：JCYJ20220531091409022）