燥与湿是中医理论中的重要概念，既是六淫的组成，也可指证候表现。燥与湿为反映机体津液盛衰的两种状态，具有相伴而生、相互转化的特点。特应性皮炎为临床常见皮肤病，具有病程长、易复发等特点，其发病与燥邪和湿邪密切相关，病症表现以燥湿同病为特点。该文通过结合现代医家对特应性皮炎的认识及多年临证经验，提出燥湿互化是特应性皮炎的重要病机，治法可采用从燥论治兼以治湿，或从湿论治兼以治燥。健脾祛湿常用茯苓、白术、陈皮、苍术、淮山、太子参、党参等；滋阴润燥可选用沙参、生地黄、石斛、麦冬等。基于中医燥湿互化病机探讨特应性皮炎的治疗，可为其临证治疗提供参考。

Dryness and dampness are important concepts in the theory of traditional Chinese medicine（TCM），which are the two factors of the six excesses and can also refer to the manifestation of symptoms. Dryness and dampness reflect the decline or abundance of body fluid，with the characteristics of existing together and mutual transformation. Atopic dermatitis is a common clinical skin disease with a long course and being easy to recur. Its onset is closely related to the pathogens of dryness and dampness，and its clinical manifestations are characterized by coexistence of dryness syndrome and dampness syndrome. In this paper，the idea of dryness-dampness mutual transformation being the important pathogenesis of atopic dermatitis was put forward after analyzing the views of modern practitioners for atopic dermatitis and based on years of clinical experience. It is proposed that atopic dermatitis can be treated from the perspective of dryness assisting with treatment for dampness，or from the perspective of dampness assisting with treatment for dryness. Herbs of Poria， Atractylodis Macrocephalae Rhizoma，Citri Reticulatae Pericarpium，Atractylodis Rhizoma，Dioscoreae Rhizoma，Pseudostellariae Radix and Codonopsis Radix are commonly used for invigorating spleen and removing dampness. And for nourishing yin to moisten dryness，herbs of Adenophorae Radix，Rehmanniae Radix，Dendrobii Caulis，and Ophiopogonis Radix are frequently adopted. The idea of treating atopic dermatitis from the pathogenesis of dryness-dampness mutual transformation in TCM will provide reference for its clinical treatment.

R275.9

国家自然科学基金项目 （编号：81704087，82274537）；陕西省重点产业链项目 （编号：2021ZDLSF04-12）；中华中医药学会雏鹰计划中医临床青年人才研修项目 （第一期）（编号：CYJH202457）