【目的】分析子午流注开穴法低频治疗儿童低度近视的临床疗效。 【方法】采用回顾性研究方法，收集2021年1月至2022年12月在广东省中医院门诊接受治疗的84例 （168眼） 低度近视患儿的临床资料。根据治疗方案的不同将患儿分成2组，将针刺联合常规验光配镜矫正治疗的42例 （84眼） 患儿作为对照组，将子午流注开穴法低频治疗联合常规验光配镜矫正治疗的42例 （84眼） 患儿作为观察组，2组治疗周期均为24周。观察2组患儿治疗前后屈光度和眼轴长度的变化情况，并评价2组患儿的临床疗效。 【结果】（1） 治疗后，2组患儿的屈光度比较，差异有统计学意义 （P＜0.05） 。2组患儿屈光度治疗前后差值比较，差异有统计学意义 （P＜0.05） 。 （2） 治疗后，2组患儿的眼轴长度比较，差异有统计学意义 （P＜0.05） 。2组患儿眼轴长度治疗前后差值比较，差异有统计学意义 （P＜0.05） 。 （3） 对照组总有效率为84.52% （71/84） ，观察组总有效率为63.10% （53/84） ，对照组疗效明显优于观察组，差异有统计学意义 （P＜0.05） 。 【结论】针刺疗法及子午流注开穴法低频治疗儿童低度近视，均可有效延缓患儿的近视程度，减缓眼轴增长速度，疗效可靠。

Objective To analyse the clinical efficacy of low-frequency of midnight-noon ebb-flow acupuncture-opening method （also called Ziwu Liuzhu Acupuncture，referring to the needling method based on acupoints selection according to qi and blood movement following heavenly-stems and earthly-branches cycle） in treating low myopia in children. Methods A retrospective study was conducted to collect the clinical data of 84 cases （168 eyes） of children with low myopia who received treatment at the Outpatient Department of Guangdong Provincial Hospital of Chinese Medicine from January 2021 to December 2022. The children were divided into two groups according to the different treatment protocols： 42 cases （84 eyes） treated with acupuncture combined with conventional optometry as the control group，and 42 cases （84 eyes） treated with low-frequency of midnight-noon ebb-flow acupuncture-opening method combined with conventional optometry as the observation group，and the treatment course of both groups was 24 weeks. The changes of refractive error and axial length before and after treatment were observed，and the clinical efficacy in the two groups of children were evaluated. Results （1） After treatment，there being statistically significant differences in the refractive error between the two groups of the children （P＜0.05） ，and the differential value of the refractive error of the children between the two groups before and after treatment was statistically significant （P＜0.05） . （2） After treatment，there being statistically significant differences in the axial length of the children in both groups （P＜0.05） . The differential value of axial lengths of the children between the two groups before and after treatment was statistically significant （P＜0.05） . （3） The total effective rate of the observation group was 84.52% （71/84） ，and which of the control group was 63.10% （53/84） ，the efficacy of the observation group was significantly superior to that of the control group， and the difference was statistically significant （P＜0.05） . Conclusion The low-frequency of midnight-noon ebb-flow acupuncture-opening method in treating low myopia in children can effectively postpone the degree of myopia，and decrease the growth of the axis，with exact therapeutic effect.

R246.9

国家中医药管理局中医药循证能力建设项目 （编号：2019XZZX-YK003）；张梅芳全国名老中医药专家传承工作室项目 （编号：201420）