[关键词]
[摘要]
【目的】探讨多囊卵巢综合征 (PCOS) 患者中医证型与其饮食、睡眠、运动等生活方式及情绪因素的相关性,为指导PCOS患者生活方式调整和治疗提供依据。 【方法】对2020年1月至2023年2月在首都医科大学附属北京中医医院就诊的已确诊为PCOS且符合纳入与排除标准的234例患者进行问卷调查,收集相关信息,包括一般资料、饮食、睡眠、运动、心理状态等,并按证候及舌脉情况辨证分为脾虚痰湿型、肾虚肝郁型、肾虚血瘀型、痰瘀互结型等4型。分析PCOS患者的中医证型分布情况,并运用统计学方法,分析不同中医证型PCOS患者的基本情况、饮食、睡眠、运动、情绪等生活方式的异同,以探讨上述因素与中医证型的关系。 【结果】(1) 中医证型分布方面,234例PCOS患者中,以脾虚痰湿型最多,共104例 (占44.4%) ,其他从高到低依次为肾虚肝郁型85例 (占36.3%) 、痰瘀互结型28例 (占12.0%) 、肾虚血瘀型17例 (占7.3%) 。 (2) 中医证型与饮食、睡眠、运动等生活方式及情绪因素的相关性方面,不同中医证型PCOS患者的体质量指数 (BMI) 、饮食偏嗜、五味偏嗜、是否有运动习惯、运动频率、运动时间、运动方式、运动强度、从上床到入睡时间、睡眠时间、情绪是否平和、是否焦虑、是否急躁易怒比较,差异均有统计学意义 (P<0.05或P<0.01) ;不同中医证型PCOS患者的年龄、学历、职业、家族史、减重史、饮食一般情况、睡眠质量、入睡时间、熬夜频率、抑郁、强迫、健忘、疲倦、自觉工作学习压力大比较,差异均无统计学意义 (P>0.05) 。 【结论】健康的生活方式对于PCOS的防治具有重要的现实意义。通过调查PCOS患者中医证型与饮食、睡眠、运动、心理状态之间的联系,明确上述危险因素与中医证型之间的相关性,可使医生对不同中医证型PCOS患者的生活方式调整指导更有针对性,对不同中医证型PCOS患者的针对性诊治有积极意义。
[Key word]
[Abstract]
Objective To preliminarily explore the correlation between traditional Chinese Medicine(TCM) syndrome types of patients with polycystic ovary syndrome (PCOS) and their lifestyle and emotional factors such as diet,sleep and exercise,thus to provide more information for guiding the treatment and lifestyle correction for patients with PCOS. Methods A questionnaire survey was conducted in 234 patients who were diagnosed with PCOS and meet the inclusion and exclusion criteria of the study at Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,from January 2020 to February 2023. The collection of relevant information covered general information, diet, sleep, exercise, and psychological state. And then the patients were differentiated as four TCM syndrome types,namely spleen deficiency and phlegm-damp type,kidney deficiency and liver constraint type, kidney deficiency and blood stasis type, phlegm blended with blood stasis type according to the symptoms as well as tongue manifestation and pulse condition. The distribution of the TCM syndrome types in PCOS was investigated,and the lifestyle factors of general information,diet,sleep,exercise,and emotions in PCOS patients with various TCM syndrome types were analyzed by statistical methods,aiming to explore the relationship between the lifestyle factors and TCM syndrome types. Results (1) The analysis of the distribution of TCM syndrome types showed that among the 234 PCOS patients,104 cases (accounted for 44.4%) were differentiated as spleen deficiency and phlegm-damp type,which was the predominant type,and then came kidney deficiency and liver constraint type 85 cases accounting for 36.3% phlegm blended with blood stasis type(28 cases,accounting for 12.0%),and kidney deficiency and blood stasis type (17 cases,accounting for 7.3%)in descending order. (2) The correlation of TCM syndrome types with lifestyle factors such as diet,sleep and exercise and emotional factors showed that statistically significant differences were presented in the body mass index(BMI), dietary preference, five-flavor preference, having or not having exercise habits, exercise frequency,duration of exercise,exercise mode,exercise intensity,time from going to bed to falling asleep, duration of sleep,emotions being or not being calm,presence of anxiety or not,and presence of impatience and irritability or not in PCOS patients with various TCM syndrome types (P<0.05 or P<0.01) . However,there were no statistically significant differences in the age,education level,occupation,family history,history of weight loss,dietary condition,sleep quality,time to fall asleep,frequency of staying up late,depression,obsessive-compulsive disorder,forgetfulness,fatigue,and self-consciousness of high pressure from work and study in PCOS patients with various TCM syndrome types (P>0.05) . Conclusion Healthy lifestyle is of great practical significance for the prevention and treatment of PCOS. The investigation of the correlation of TCM syndrome types with diet,sleep,exercise and psychological state of PCOS patients reveals the possible risk factors for TCM syndromes in PCOS,which will enable the practitioners to perform targeted lifestyle correction for PCOS patients with different TCM syndrome types,and has positive significance for targeted diagnosis and treatment of PCOS patients with different TCM syndrome types.
[中图分类号]
R271.9
[基金项目]
北京市中医药科技发展基金资助项目 (编号:JJ-2020-47)