【目的】探究多囊卵巢综合征 （PCOS） 患者出生日期的五运六气及四时节律与其后天疾病罹患之间的关系。 【方法】收集2016年3月至2023年3月期间在河南中医药大学第一附属医院生殖医学科二病区门诊就诊的321例PCOS患者的临床资料，对患者出生日期的五运六气及四时节律进行统计分析。 【结果】321例PCOS患者的出生日期的季节分布及五运六气的客运、主气、客气、司天、在泉分布比较，差异均无统计学意义 （P＞0.05） 。而天干、岁运及主运分布比较，差异均有统计学意义（P＜0.05或P＜0.01） ，其中，天干为己年的最多，占总人数的13.1% （42/321） ；岁运为少土之运的最多，占总人数的13.1%（42/321） ；主运为少水之运的最多，占总人数的15.9% （51/321） 。 【结论】PCOS的罹患与其出生日期的四时节律无明显相关性，与其五运六气的天干、岁运及主运相关：出生日期天干为己年、岁运为少土之运、主运为少水之运者，后天罹患PCOS的可能性较大。

Objective To investigate the relationship of the five-circuit and six-qi features and seasonal rhythm of the birth date of patients with polycystic ovary syndrome （PCOS） with the postnatal incidence of PCOS. Methods Clinical data collection was carried out in 321 PCOS patients who attended the outpatient clinic of Second Department of Reproductive Medicine，the First Affiliated Hospital of Henan University of Chinese Medicine from March 2016 to March 2023，and then the five-circuit and six-qi features and seasonal rhythm of the birth date of PCOS patients were statistically analyzed. Results There were no statistically significant differences in the seasonal distribution of the birth date and in the distribution of five-circuit and six-qi indicators of guest circuit，predominant qi，guest qi，sitian （celestial control，circuit qi of the first half of a year） ，and zaiquan （terrestrial effect，circuit qi of the second half of a year） of the 321 patients with PCOS （P＞0.05），where there were statistically significant differences in the distribution of five-circuit and six-qi indicators of heavenly stems，yearly circuit，and predominant circuit （P＜0.05 or P＜0.01） . Birth year of ji（the 6th of the ten heavenly stems） year was predominated in the heavenly stems，and the patients accounted for 13.1%（42/321）；the deficient earth circuit was predominated in the yearly circuit，and the patients accounted for 13.1% （42/321） ；the deficient water circuit was predominated in the predominant circuit，and the patients accounted for 15.9% （51/321） . Conclusion No significant correlation exists between the incidence of PCOS and seasonal rhythm of birth date of the patients. However，the incidence of PCOS is correlated with the five-circuit and six-qi indicators of heavenly stems，yearly circuit，and predominant circuit，and a higher likelihood of suffering from PCOS occurs in the population born in the heavenly-stem ji year，in the yearly circuit being deficient earth circuit，in the predominant circuit being deficient water circuit.

R271.9

国家自然科学基金资助项目 （编号：82074167）