【目的】 观察通元针法联合加味苓桂术甘汤治疗脾虚痰湿型多囊卵巢综合征（PCOS）的临床疗效。【方法】 将86例脾虚痰 湿型PCOS患者随机分为观察组和对照组，每组各43例。对照组给予盐酸二甲双胍联合炔雌醇环丙孕酮片治疗，观察组在对 照组治疗的基础上，给予通元针法联合加味苓桂术甘汤治疗，2组患者均持续治疗 3个月。治疗 3个月后，评价 2组临床疗 效，观察 2 组患者治疗前后性激素指标雌二醇（E2）、睾酮（T）、促黄体生成激素（LH）、促卵泡生成激素（FSH）、催乳激素 （PRL）表达水平的变化情况，比较 2组患者治疗前后糖代谢水平包括胰岛素抵抗指数（HOMA-IR）、空腹胰岛素（FINS）、空 腹血糖（FPG）表达水平的变化情况。【结果】（1）观察组总有效率为90.70%（39/43），对照组为74.42%（32/43）。观察组疗效优 于对照组，差异有统计学意义（P＜0.05）。（2）治疗后，2组患者的HOMA-IR、FINS、FPG水平均明显改善（P＜0.05），且观察 组在改善 HOMA-IR、FINS、FPG 水平方面明显优于对照组，差异有统计学意义（P＜0.05）。（3）治疗后，2 组患者 E2、T、 LH、FSH、PRL水平均明显改善（P＜0.05），且观察组在改善患者 E2、T、LH、FSH、PRL水平方面明显优于对照组，差异 均有统计学意义（P＜0.05）。【结论】 通元针法联合加味苓桂术甘汤治疗脾虚痰湿型PCOS，可有效改善患者性激素水平，调节 患者机体糖代谢，临床疗效显著。

Objective To observe the clinical effect of Tongyuan Acupuncture combined with Modified Linggui Zhugan Decoction in the treatment of polycystic ovary syndrome（PCOS）with spleen deficiency and phlegm-damp syndrome. Methods A total of 86 patients with PCOS of spleen deficiency and phlegm-damp type were randomly divided into observation group and control group， 43 cases in each group. The control group was treated with Metformin Hydrochloride Tablets combined with Ethinylestradiol and Cyproterone Acetate Tablets. The observation group was treated with Tongyuan Acupuncture combined with Modified Linggui Zhugan Decoction on the basis of the treatment of the control group. Both groups were treated for three consecutive months. After three months of treatment， the clinical efficacy of the two groups was evaluated. The changes of sex hormone indexes estradiol （E2），testosterone（T），luteinizing hormone（LH），follicle stimulating hormone（FSH）and prolactin（PRL） expression levels were observed before and after treatment in the two groups. The changes of glucose metabolism levels including insulin resistance index（HOMA-IR），fasting insulin（FINS）and fasting blood glucose（FPG） expression levels were compared before and after treatment between the two groups. Results（1）The total effective rate was 90.70%（39/43）in the observation group and 74.42%（32/43）in the control group. The curative effect of the observation group was superior to that of the control group，and the difference was statistically significant（P＜ 0.05）.（2）After treatment，HOMA-IR，FINS and FPG in the two groups were significantly improved（P＜0.05）， and the improvement of HOMA-IR，FINS and FPG in the observation group was superior to that in the control group，the difference being significant（P＜0.05）.（3）After treatment，the levels of E2，T，LH，FSH and PRL in the two groups were significantly improved（P＜0.05），and the levels of E2，T，LH，FSH and PRL in the observation group were significantly superior to those in the control group， the differences were statistically significant（P＜0.05）. Conclusion Tongyuan Acupuncture combined with Modified Linggui Zhugan Decoction in the treatment of spleen deficiency and phlegm-damp type of PCOS can effectively improve the sex hormone level of patients and regulate the glucose metabolism of patients. The clinical effect is significant.

R246.9

广东省中医药管理局科研资助项目（编号：20241246）；佛山市科技局科研资助项目（编号：2220001004227）；广东省教育厅普通 高校认定类科研项目（编号：2021WQNCX205）