【目的】观察腰椎定点扳法联合磁圆针治疗腰椎间盘突出症的临床疗效。 【方法】将60例腰椎间盘突出症患者随机分为 治疗组和对照组，每组各30例，治疗组给予腰椎定点扳法联合磁圆针治疗，对照组给予塞来昔布胶囊治疗。治疗2周为1个 疗程，连续治疗2个疗程。治疗1个月后，评价2组临床疗效，观察2组患者治疗前后视觉疼痛模拟评分法 （VAS） 评分的变化 情况，以及日本骨科协会 （JOA） 评分的变化情况。比较2组患者治疗前后血清核因子κB （NF-κB） p65、肿瘤坏死因子α （TNF-α） 、白细胞介素6 （IL-6） 的变化情况。 【结果】（1） 治疗后，2组患者的JOA评分和VAS评分均明显改善 （P＜0.05） ，且 观察组在改善JOA评分和VAS评分方面明显优于对照组，差异均有统计学意义 （P＜0.05） 。 （2） 治疗后，2组患者的NF-κB p65、 血清IL-6和TNF-α含量均明显改善 （P＜0.05） ，且观察组在改善NF-κB p65、血清IL-6和TNF-α含量方面明显优于对照组， 差异均有统计学意义 （P＜0.05） 。 （3） 治疗组总有效率为86.67% （26/30） ；对照组为50.00% （15/30） ，治疗组疗效明显优于对照 组，差异有统计学意义 （P＜0.05） 。 【结论】腰椎定点扳法联合磁圆针治疗腰椎间盘突出症，能够有效缓解患者的疼痛症状， 改善患者的腰椎功能，有效降低血清NF-κB p65、IL-6和TNF-α的水平，临床疗效显著。

Objective To observe the clinical effect of lumbar fixed-point pulling method combined with magnetic needling in the treatment of lumbar disc herniation （LDH） . Methods Sixty LDH patients were randomly divided into treatment group and control group，30 cases in each group. The treatment group was treated with lumbar fixed- point pulling method combined with magnetic needling，and the control group was treated with Celecoxib Capsules. Two weeks as a course of treatment and both groups were treated for two courses. After 1 month of treatment，the clinical efficacy of the two groups was evaluated，and the changes of Visual Analogue Scale（VAS） score and Japanese Orthopaedic Association （JOA） score were observed before and after treatment in the two groups. The changes of serum nuclear factor-κB （NF-κB） p65，tumor necrosis factor-α （TNF-α） and interleukin-6 （IL-6） were compared between the two groups before and after treatment. Results （1） After treatment，the JOA score and VAS score of the two groups were significantly improved （P＜0.05） ，and the improvement of JOA score and VAS score in the observation group was significantly superior to that in the control group， the differences were statistically significant （P＜0.05） . （2） After treatment，the contents of NF-κB p65，serum IL-6 and TNF-α in the two groups were significantly improved （P＜0.05），and the improvement of NF- κB p65，serum IL-6 and TNF- α in the observation group was significantly superior to that in the control group，the differences were statistically significant （P＜0.05） . （3） The total effective rate of the treatment group was 86.67%（26/30）；the control group was 50.00% （15/30） . The curative effect of the treatment group was significantly superior to that of the control group，and the difference was statistically significant（P＜0.05） . Conclusion Lumbar fixed-point pulling method combined with magnetic needling in the treatment of LDH can effectively relieve the pain symptoms of patients，improve the lumbar function of patients，and effectively reduce the levels of serum NF-κB p65，IL-6 and TNF-α. The clinical effect is significant.

R246.9

湖南省中医药管理局一般项目 （编号：D2022034）