【目的】观察电针水沟穴联合温针灸治疗急性脑梗死的临床疗效。 【方法】将96例急性脑梗死患者随机分为观察组和对 照组，每组各48例。2组患者均给予常规基础治疗，对照组给予温针灸治疗，观察组在对照组治疗的基础上，给予电针水沟 穴治疗。每周治疗5 d，共治疗3周。治疗3周后，评价2组临床疗效，观察2组患者治疗前后美国国立卫生研究院的卒中量 表 （NIHSS） 评分、日常生活活动能力 （Barthel Index，BI） 量表评分以及Fugl-Meyer运动功能评估量表评分的变化情况。比较 2组患者治疗前后白细胞介素6 （IL-6） 、超敏C反应蛋白 （hs-CRP） 、同型半胱氨酸 （Hcy） 水平的变化情况。并评价2组的安全 性及不良反应的发生情况。 【结果】（1） 观察组总有效率为95.83% （46/48） ，对照组为81.25% （39/48） 。观察组疗效优于对照 组，差异有统计学意义 （P＜0.05） 。 （2） 治疗后，2组患者的NIHSS评分、BI评分、FMA评分均明显改善 （P＜0.05） ，且观察组 在改善NIHSS评分、BI评分、FMA评分方面明显优于对照组，差异有统计学意义 （P＜0.05） 。 （3） 治疗后，2组患者的血清 IL-6、hs-CRP、Hcy水平均明显改善 （P＜0.05） ，且观察组在改善血清炎性因子的IL-6、hs-CRP以及Hcy水平方面明显优于 对照组，差异有统计学意义 （P＜0.05） 。 （4） 观察组与对照组的不良反应发生率比较，差异无统计学意义 （P＞0.05） 。 【结论】电 针水沟穴联合温针灸治疗急性脑梗死，可明显促进患者的神经功能恢复，从而改善患者的运动和生活能力，有效降低炎性 因子和同型半胱氨酸水平，临床疗效显著。

Objective To observe the clinical efficacy of electroacupuncture at Shuigou（DU26） combined with warming-needle moxibustion in the treatment of acute cerebral infarction. Methods Nighty-six patients with acute cerebral infarction were randomly divided into observation group and control group，48 cases in each group. Both groups were given routine basic treatment. The control group was treated with warming-needle moxibustion. The observation group was treated with electroacupuncture at Shuigou point on the basis of the control group. The treatment was performed 5 days a week for a total of 3 weeks. After 3 weeks of treatment，the clinical efficacy of the two groups was evaluated，and the changes of National Institutes of Health Stroke Scale（NIHSS） score，Barthel Index （BI） score and Fugl-Meyer motor function assessment scale score of the two groups were observed before and after treatment. The changes of interleukin-6 （IL-6）， high-sensitivity C-reactive protein（hs-CRP） and homocysteine （Hcy） levels were compared before and after treatment between the two groups. The safety and adverse reactions of the two groups were evaluated. Results （1） The total effective rate of the observation group was 95.83%（46/48），and that of the control group was 81.25%（39/48） . The efficacy of the observation group was superior to that of the control group，and the difference was statistically significant （P＜0.05） . （2） After treatment， the NIHSS scores，BI scores，and FMA scores of the patients in the two groups were significantly improved （P＜ 0.05），and the observation group was significantly superior to the control group in improving the NIHSS scores， BI scores，and FMA scores，with a statistically significant difference（P＜0.05） . （3） After treatment，the serum IL-6，hs-CRP，and Hcy levels of patients in the two groups were significantly improved （P＜0.05），and the observation group was significantly superior to the control group in improving the serum inflammatory factors of IL-6， hs-CRP， and Hcy levels， with statistically significant differences（P＜0.05） . （4）Comparing the incidence of adverse reactions between the observation group and the control group， the difference was not statistically significant（P＞0.05） . Conclusion Electroacupuncture at Shuigou point combined with warming- needle moxibustion in the treatment of acute cerebral infarction can significantly promote the recovery of patients’ neurological function，thus improving their motor and living ability，effectively reducing the levels of inflammatory factors and homocysteine，and the clinical efficacy is remarkable.

R246.9

海南省科技厅重点研发基金资助项目 （编号：ZDYF2022SHFZ129）；海南省临床医学研究中心中医康复学资助项目[编号：三财 社 （2023） 82号]；三亚市刘建浩名医工作室资助项目