[关键词]
[摘要]
通过数据挖掘探索电针治疗糖尿病周围神经病变(DPN)的常用腧穴及刺激参数。【方法】 检索中国知网期刊全 文数据库(CNKI)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊数据库(VIP)、中国生物医学数据库(CBM)、美 国生物医学信息检索系统(PubMed)自建库至2023年5月收录的电针治疗DPN的临床研究文献,建立电针治疗DPN的选穴处 方及电针刺激参数数据库,对数据进行描述性统计、聚类分析与关联规则分析。【结果】 对纳入的36篇文献中的36首处方进 行分析,使用频次较高的前 3位腧穴为:三阴交、足三里、合谷;腧穴归经以足太阳膀胱经、足阳明胃经、足太阴脾经为 主;聚类分析得出8个聚类集群;关联规则分析得到“合谷、足三里、三阴交”的核心处方,其中支持度最高的穴位组合是 “足三里-三阴交”。最常使用的刺激参数为:连续波、疏密波,5 Hz,强度耐受,30 min/次,1次/d,总治疗时间4周。【结论】 电针治疗DPN的核心穴组为合谷、足三里、三阴交;电针参数推荐5 Hz,连续波,30 min/次,1次/d,治疗4周。可为电针 治疗DPN的临床取穴及参数选择提供一定的参考依据。
[Key word]
[Abstract]
To explore the commonly used acupoints and stimulation parameters of electroacupuncture in the treatment of diabetic peripheral neuropathy(DPN) through data mining. Methods The clinical research literature of electroacupuncture in the treatment of DPN was retrieved from CNKI, Wanfang, VIP, CBM and PubMed from the establishment of the database to May 2023. The database of acupoint selection and electroacupuncture stimulation parameters for electroacupuncture in the treatment of DPN was established. Descriptive statistics, cluster analysis and association rule analysis were performed on the data. Results The 36 prescriptions in the 36 included literatures were analyzed. The top three acupoints with high frequency of use were:Sanyinjiao(SP6),Zusanli(ST36) and Hegu(LI4);acupoints are mainly bladder meridian of foot bladder meridian,stomach meridian of foot yangming,spleen meridian of foot taiyin;through cluster analysis,8 cluster clusters were obtained. The core prescription of ‘Hegu,Zusanli,Sanyinjiao’ was obtained by association rule analysis, and the most supported acupoint combination was ‘Zusanli-Sanyinjiao’. The most commonly used stimulation parameters were continuous wave,density wave,5 Hz,intensity tolerance,30 minures/time,1 time/ day, and the total treatment time was 4 weeks. Conclusion The core acupoints of electroacupuncture in the treatment of DPN are Hegu, Zusanli and Sanyinjiao. Electroacupuncture parameters recommended 5 Hz, continuous wave,30 minutes/time,1 time/day,treatment for 4 weeks. It can provide some reference for clinical acupoint selection and parameter selection of electroacupuncture in the treatment of DPN.
[中图分类号]
R246.9
[基金项目]
广东省中医药局中医药科研资助项目(编号:20241332)