观察化瘀生新合剂（由黄芪、当归、党参、川芎、桃仁、益母草、白术、炮姜、炙甘草等9味中药组成）联合雷 火灸对促进人工流产术（简称人流术）后子宫内膜修复、预防宫腔粘连的临床疗效。【方法】 将60例确诊为早期宫内妊娠并自 愿行人流术的患者随机分为对照组和观察组，每组各30例。对照组给予雌激素疗法治疗，即于人流术后当天开始予以口服 补佳乐治疗，观察组在对照组的基础上给予化瘀生新合剂联合雷火灸（取穴：中极、神阙、关元、双侧子宫、双侧归来）治 疗。观察2组患者的子宫恢复情况、子宫动脉血流情况、子宫结合带连续性情况以及不良反应发生情况。【结果】（1）子宫恢 复情况：与对照组相比，观察组的阴道流血时间和月经复潮时间明显缩短，子宫内膜厚度明显增厚，差异均有统计学意义 （P＜0.01）。（2）子宫动脉血流情况：观察组两侧的子宫动脉搏动指数（PI）、阻力指数（RI）及收缩期最大血流速度/舒张末期血 流速度（S/D）平均数值均较对照组好，但除右侧子宫动脉 S/D 外，差异均无统计学意义（P＞0.05）。（3）子宫结合带连续性情 况：与对照组相比，观察组的子宫结合带中断例数较对照组少，连续性情况明显优于对照组，差异有统计学意义（P＜0.05）。 （4）不良反应发生情况：治疗期间，2组患者均无出现严重的不良反应，具有较高的安全性。【结论】 人流术后在雌激素疗法 基础上加用化瘀生新合剂联合雷火灸治疗，能更有效促进子宫内膜修复，从而更好地预防宫腔粘连。

To observe the clinical effect of Huayu Shengxin Mixture （composed of Astragali Radix， Angelicae Sinensis Radix， Codonopsis Radix， Chuanxiong Rhizoma， Persicae Semen， Leonuri Herba， Atractylodis Macrocephalae Rhizoma， Zingiberis Rhizoma Praeparatum， and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle） combined with thunder-fire moxibustion on promoting endometrial repair and preventing intrauterine adhesions after induced abortion. Methods Sixty patients diagnosed as early intrauterine pregnancy and voluntarily to take abortion were randomly divided into control group and observation group，with 30 cases in each group. The control group was given estrogen therapy by oral use of Progynova starting from the day of induced abortion，and the observation group was given Huayu Shengxin Mixture combined with thunder-fire moxibustion on acupoints of Zhongji（CV3）， Shenque（CV8）， Guanyuan（CV4）， bilateral Zigong（Ex-CA07）， and bilateral Guilai（ST29） on the basis of treatment for the control group. The repair of endometrium，uterine artery blood flow， the continuity induced of uterine junctional zone and the incidence of adverse reactions of the two groups were observed. Results （1） For the repair of endometrium， the vaginal bleeding time and time for the return of menses in the observation group were significantly shortened and the endometrial thickness was significantly thickened as compared with those in the control group， and the differences were statistically significant （P＜0.05）.（2） The improvement of uterine artery blood flow indicators of bilateral uterine artery pulsatility index（PI）， resistance index（RI）and the mean values of the ratio of peak systolic velocity to end diastolic velocity（S/D） in the observation group was superior to that in the control group，but the differences of the uterine artery blood flow indicators except for S/D of the right uterine artery were all insignificant（P＞0.05）.（3）In terms of the continuity of uterine junctional zone，the patients with the interruption of uterine junctional zone in the observation group were less than those in the control group，indicating that the continuity of uterine junctional zone was significantly superior to that in the control group and the difference was statistically significant（P＜0.05）.（4） During the treatment， there were no serious adverse reactions occurring in the two groups， with high safety. Conclusion The treatment with the combination of Huayu Shengxin Mixture and thunder-fire moxibustion on the basis of post-abortion estrogen therapy is more effective on promoting the repair of endometrium and preventing intrauterine adhesions.

R271.9

广东省中医药局科研项目（编号：20231414）