基于FangNet平台，对全国名中医刘茂才治疗中风病后遗症的有效病案的处方资料进行药物频次、性味归经的统计， 并通过分析处方药物的权重等级、药物共现性与互斥性、药物-症状关联规则以及药物聚类，总结刘茂才教授治疗中风病后 遗症的用药规律。结果共得到105首处方，涉及95味中药。处方用药以性温、味甘、入肝经的药物为主。挖掘得到17味主 药，分别为黄芪、天麻、山茱萸、党参、杜仲、牛膝、川芎、远志、姜黄、石菖蒲、麦冬、白术、丹参、茯苓、钩藤、法 半夏、女贞子。药物共现性分析结果得到牛膝-杜仲等12对药对，药物-症状关联规则分析得到天麻-头晕等9组药物-症状 关联组合，聚类分析得到4个药物组合。分析结果提示刘茂才教授治疗中风病后遗症用药温和，以扶正补虚的药物为主，常 以黄芪、党参大补元气，山茱萸、牛膝、杜仲等补益肝肾，同时兼顾痰瘀同治，攻补兼施。

Based on FangNet platform，the data of the prescriptions for the effective cases of post-stroke sequelae treated by national renowned Chinese medical practitioner LIU Mao- Cai were collected for the analysis of medication frequency of the prescribed drugs as well as their properties， flavors and meridian tropism. The medication rules of LIU Mao-Cai for treating post-stroke sequelae was summarized by analyzing the weight scale， co-occurrence and mutual exclusivity of the prescribed drugs and by drug-symptom association rule analysis and drug clustering analysis. The results showed that a total of 105 prescriptions involving 95 Chinese medicines were obtained. The drugs in the prescriptions were mainly warm in nature，sweet in flavor and had the meridian tropism of liver meridian. There were 17 driver herbs， and they were Astragali Radix， Gastrodiae Rhizoma， Corni Fructus， Codonopsis Radix， Eucommiae Cortex， Achyranthis Bidentatae Radix， Chuanxiong Rhizoma， Polygalae Radix， Curcumae Longae Rhizoma， Acori Tatarinowii Rhizoma， Ophiopogonis Radix， Atractylodis Macrocephalae Rhizoma， Salviae Miltiorrhizae Radix et Rhizoma， Poria， Uncariae Ramulus cum Uncis， Pinelliae Rhizoma Praeparatum，and Ligustri Lucidi Fructus. The results of drug co-occurrence analysis yielded 12 drug pairs such as Achyranthis Bidentatae Radix-Eucommiae Cortex，drug-symptom association rule analysis yielded 9 groups of drug-symptom association combinations such as Gastrodiae Rhizoma-dizziness，and cluster analysis yielded 4 drug combinations. The results indicated that the drugs for post-stroke sequelae treated by LIU Mao-Cai are mild in nature and mainly have the actions of supporting healthy-qi and replenishing the deficient， and Astragali Radix and Codonopsis Radix are often used to replenish the vital energy， and Corni Fructus， Achyranthis Bidentatae Radix and Eucommiae Cortex are usually used to tonify the liver and kidney. Moreover， simultaneous treatment of phlegm and blood stasis， and simultaneous application of purging and nourishing therapeutics are also stressed.

R255.2

国家重点研发计划项目——基于“道术结合”思路与多元融合方法的名老中医经验传承创新研究（编号：2018YFC1704100）； 东部地区名老中医学术观点、特色诊疗方法和重大疾病防治经验研究项目（编号：2018YFC1704102）