[关键词]
[摘要]
观察针刺内迎香加自拟鼻炎方联合西药治疗肺气虚寒型鼻鼽的临床疗效。【方法】将60例肺气虚寒型鼻鼽患者 随机分为观察组与对照组,每组各30例,对照组给予地氯雷他定片联合糠酸莫米松鼻喷雾剂治疗,观察组在对照组治疗的 基础上,给予针刺内迎香联合自拟鼻炎方治疗。2组均治疗14 d。治疗14 d后,评价2组临床疗效。观察2组患者治疗前后 鼻部症状评分的变化情况,以及视觉模拟量表(VAS)和鼻结膜炎生活质量调查问卷(RQLQ)评分的情况。比较2组患者治疗 前后中医证候积分以及血清免疫球蛋白E(IgE)的变化情况。并评价2组的安全性。【结果】(1)观察组总有效率为93.33% (28/30),对照组为73.33%(22/30)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者鼻塞、喷 嚏、流涕及鼻痒症状均明显改善(P<0.01),且观察组在改善鼻部症状方面明显优于对照组,差异有统计学意义(P<0.05)。 (3)治疗后,2组患者VAS评分明显改善(P<0.01),且观察组在改善VAS评分方面优于对照组,差异有统计学意义(P< 0.05)。(4)治疗后,2组患者PQLQ评分明显改善(P<0.01),且观察组在改善PQLQ评分方面明显优于对照组,差异有统计学 意义(P<0.05)。(5)治疗后,2组患者中医证候积分均明显改善(P<0.01),且观察组在改善中医证候积分方面明显优于对照 组,差异有统计学意义(P<0.05)。(6)治疗后,2组患者血清IgE水平明显改善(P<0.01),且观察组在改善血清IgE水平方面 明显优于对照组,差异有统计学意义(P<0.05)。(7)观察组与对照组的不良反应发生率比较,差异无统计学意义(P>0.05)。 【结论】针刺内迎香加自拟鼻炎方联合西药治疗肺气虚寒型鼻鼽,可明显改善患者的临床症状,从而提高患者的生活质量, 疗效显著。
[Key word]
[Abstract]
To observe the clinical efficacy of acupuncture at Neiyingxiang(EX-HN09)points combined with western medicine in the treatment of allergic rhinitis of deficiency- cold of lung qi type. Methods Sixty patients with deficiency-cold of lung qi type of allergic rhinitis were randomly divided into observation group and control group,with 30 patients in each group. The control group was treated with Desloratadine Tablets combined with Mometasone Furoate Aqueous Nasal Spray, and the observation group was treated with acupuncture at Neiyingxiang points combined with the self-made rhinitis recipe on the basis of the control group,and the clinical efficacy of the two groups was evaluated after 14 days. The changes of nasal symptom scores, Visual Analogue Scale(VAS)and rhinoconjunctivitis quality of life scores of the patients of the two groups were observed before and after the treatment. After 14 days of treatment,the clinical efficacy of the two groups was evaluated. The changes in nasal symptom scores,as well as VAS and rhinoconjunctivitis quality of life questionnaire(RQLQ)scores were observed before and after treatment. The changes in traditional Chinese medicine(TCM)sydnrome scores and serum immunoglobulin E(IgE)were compared before and after treatment in the two groups,and the safety of the two groups was evaluated. Results(1)The total effective rate of the observation group was 93.33%(28/30),and the control group was 73.33%(22/30). The efficacy of the observation group was superior to that of the control group, and the difference was statistically significant(P<0.05).(2)After treatment, the symptoms of nasal congestion, sneezing, runny nose and nasal itching were significantly improved in the two groups(P<0.01), and the observation group was significantly superior to the control group in improving nasal symptoms, and the differences were statistically significant(P<0.05).(3)After treatment, the VAS scores of patients in the two groups were significantly improved(P<0.01), and the observation group was superior to the control group in improving VAS scores,with statistically significant differences(P<0.05).(4)After treatment,the PQLQ scores of patients in the two groups improved significantly(P<0.01), and the observation group was significantly superior to the control group in improving the PQLQ scores,and the difference was statistically significant(P< 0.05).(5)After treatment,the TCM syndrome scores of the patients in the two groups were significantly improved (P<0.01),and the observation group was significantly superior to the control group in improving TCM syndrome scores,with statistically significant differences(P<0.05).(6)After treatment,the serum IgE levels of patients in the two groups were significantly improved(P<0.01),and the observation group was significantly superior to the control group in improving serum IgE levels(P<0.05),with a statistically significant difference.(7)There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P>0.05). Conclusion Acupuncture at Neiyingxiang points plus self-made rhinitis recipe combined with western medicine in the treatment of deficiency-cold of lung qi type of allergic rhinitis can significantly improve the clinical symptoms of the patients, thus improving the quality of life of the patients, and the therapeutic efficacy is remarkable.
[中图分类号]
R246.9
[基金项目]
山东省潍坊市中医药科研计划项目(编号:2021-1-001)